Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.60 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.60 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.60 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11498069 | 0.87 | PARP10 (0.77) | PARP10ALDH1A1PARP15PARP4PARP14 | |
| SCHEMBL25142213 | 0.86 | PARP10 (0.66) | PARP10ALDH1A1PARP15PARP4PARP14 | |
| SCHEMBL23463916 | 0.84 | ALDH1A1 (0.68) | PARP10ALDH1A1PARP15PARP4PARP14 | |
| SCHEMBL5608673 | 0.84 | HPGD (0.62) | PARP10ALDH1A1KMT2AMAPTLPAR1 | |
| SCHEMBL8746017 | 0.84 | LPAR1 (0.70) | PARP10ALDH1A1PARP15LPAR1LPAR5 | |
| SCHEMBL11604084 | 0.83 | LPAR1 (0.53) | PARP10ALDH1A1LPAR1LPAR5CYP1A2 | |
| SCHEMBL11603272 | 0.83 | LPAR1 (0.68) | PARP10ALDH1A1PARP15LPAR1LPAR5 | |
| SCHEMBL13687491 | 0.82 | PARP10 (0.59) | PARP10PARP15PARP14HPGDPARP2 | |
| Potassium Ion SCHEMBL11603948 | 0.81 | LPAR1 (0.52) | PARP10ALDH1A1LPAR1LPAR5CYP1A2 | |
| SCHEMBL11602845 | 0.81 | CA2 (0.53) | PARP10ALDH1A1LPAR1LPAR5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |