Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746017 | 0.86 | LPAR1 (0.70) | HPGDLPAR1LPAR5MAPK14EZH2 | |
| SCHEMBL11603272 | 0.84 | LPAR1 (0.68) | HPGDLPAR1LPAR5MAPK14EZH2 | |
| SCHEMBL11604084 | 0.84 | LPAR1 (0.53) | HPGDLPAR1LPAR5MAPK14EZH2 | |
| SCHEMBL11602631 | 0.84 | PARP10 (0.66) | HPGDMAPTLPAR1LPAR5MAPK14 | |
| SCHEMBL9861909 | 0.84 | MAPT (0.64) | HPGDMAPTRAB9AMAOBALDH1A1 | |
| SCHEMBL11602845 | 0.83 | CA2 (0.53) | HPGDLPAR1LPAR5MAPK14EZH2 | |
| Potassium Ion SCHEMBL11603948 | 0.83 | LPAR1 (0.52) | HPGDLPAR1LPAR5MAPK14EZH2 | |
| SCHEMBL1191950 | 0.83 | TDP1 (0.68) | MAPTRAB9ALPAR1LPAR5MAPK14 | |
| SCHEMBL5317270 | 0.83 | CA12 (0.63) | HPGDMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7690257 | 0.82 | ALDH1A1 (0.59) | HPGDRAB9ALPAR1LPAR5MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5286894-A | Phenyl acrylic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |