SCHEMBL874615

SCHEMBL874615

CCOc1ccc(C=CC(C)=O)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.66
NPC1 O15118 3/20 0.66
RAB9A P51151 3/20 0.66
TP53 P04637 2/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
KDM4E B2RXH2 3/20 0.65
ALDH1A1 P00352 2/20 0.65
KMT2A Q03164 2/20 0.65
HTT P42858 1/20 0.65
MAOB P27338 9/20 0.63
ABCG2 Q9UNQ0 1/20 0.63
MAOA P21397 1/20 0.60
SLC5A1 P13866 1/20 0.60
SLC5A2 P31639 1/20 0.60
TAS1R3 Q7RTX0 1/20 0.60
TAS1R1 Q7RTX1 1/20 0.60
MEN1 O00255 1/20 0.58
HPGD P15428 1/20 0.58
CASP7 P55210 1/20 0.58
HSD17B10 Q99714 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17212246 1.00 MAPT (0.66) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL4939430 0.86 ABCG2 (0.65) NPC1RAB9AABCG2
SCHEMBL4933533 0.86 ABCG2 (0.65) NPC1RAB9AABCG2
SCHEMBL4933565 0.86 ABCG2 (0.65) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL4933573 0.86 ABCG2 (0.65) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL691132 0.86 NPC1 (0.69) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL691131 0.86 NPC1 (0.69) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL9036957 0.85 GAA (0.57) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL9036952 0.85 GAA (0.57) MAPTNPC1RAB9ATP53SMN1; SMN2
SCHEMBL2225311 0.84 NPC1 (0.63) MAPTNPC1RAB9ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398585-B1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME HAYASHIBARA CO (JP) 2020-02-26 EP disclosed
US-10550142-B2 Quercetin-based compound AMOREPACIFIC CORPORATION (KR) 2020-02-04 US disclosed
US-20190241601-A1 NOVEL QUERCETIN-BASED COMPOUND AMOREPACIFIC CORPORATION (KR) 2019-08-08 US disclosed
US-10309212-B2 Energetic cocrystals for treatment of a subterranean formation HALLIBURTON ENERGY SERVICES, INC. (US) 2019-06-04 US disclosed
US-10253244-B2 Scale-inhibiting cocrystals for treatment of a subterranean formation HALLIBURTON ENERGY SERVICES, INC. (US) 2019-04-09 US disclosed
US-20190008747-A1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME Hayashibara Co., Ltd. (JP) 2019-01-10 US disclosed
EP-3398585-A1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME Hayashibara Co., Ltd. (JP) 2018-11-07 EP disclosed
US-10111822-B2 External dermal composition for anti-ageing and method for producing the same Hayashibara Co., Ltd. (JP) 2018-10-30 US disclosed
EP-2939657-B1 SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR HAYASHIBARA CO (JP) 2018-08-08 EP disclosed
US-10006151-B2 Polyurethane fiber TORAY OPELONTEX CO., LTD. (JP) 2018-06-26 US disclosed
EP-2292585-A1 Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound APTUIT (KANSAS CITY), LLC (US) 2011-03-09 EP disclosed
US-20090281195-A1 NOVEL COCRYSTALLIZATION S.S.C.I., INC. (US) 2009-11-12 US disclosed
US-20090087401-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-04-02 US disclosed
US-7452555-B2 Cocrystallization S.S.C.I., INC. (US) 2008-11-18 US disclosed
US-20080095721-A1 Natural sunscreen compositions and processes for producing the same HIMALAYA GLOBAL HOLDINGS LIMITED (AE) 2008-04-24 US disclosed
US-7311896-B2 Natural sunscreen compositions and processes for producing the same MMI CORPORATION (KY) 2007-12-25 US disclosed
US-20070287194-A1 Screening For Solid Forms By Ultrasound Crystallization And Cocrystallization Using Ultrasound S.S.C.I., INC 2007-12-13 US disclosed
US-20070088508-A1 Cocrystallization methods APTUIT (WEST LAFAYETTE), LLC 2007-04-19 US disclosed
US-20060165622-A1 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-27 US disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241601-A1 NOVEL QUERCETIN-BASED COMPOUND TEAD3, TEAD4, TEAD2 MAPT 237/4885NPC1 4180/4885RAB9A 1287/4885
US-10550142-B2 Quercetin-based compound TEAD3, TEAD4, TEAD2 MAPT 202/4885NPC1 4089/4885RAB9A 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.