Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746878 | 1.00 | PTGS2 (0.48) | PTGS2PTGS1NT5ERAD51MEN1 | |
| SCHEMBL9356828 | 0.92 | NT5E (0.56) | PTGS2PTGS1NT5ERAD51MEN1 | |
| SCHEMBL9356837 | 0.92 | NT5E (0.56) | PTGS2PTGS1NT5ERAD51MEN1 | |
| SCHEMBL1399781 | 0.92 | PTGS2 (0.56) | PTGS2PTGS1NT5ERAD51MEN1 | |
| SCHEMBL9360466 | 0.92 | PTGS2 (0.56) | PTGS2PTGS1NT5ERAD51MEN1 | |
| SCHEMBL1536243 | 0.91 | NT5E (0.56) | NT5ERAD51MEN1KMT2ALMNA | |
| SCHEMBL29692725 | 0.91 | NT5E (0.56) | NT5ERAD51MEN1KMT2ALMNA | |
| SCHEMBL1536241 | 0.91 | NT5E (0.56) | NT5ERAD51MEN1KMT2ALMNA | |
| SCHEMBL15859262 | 0.89 | NT5E (0.55) | NT5ERAD51MEN1KMT2ALMNA | |
| SCHEMBL2391190 | 0.89 | NT5E (0.55) | NT5ERAD51MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498217-B1 | Dyes for polarising films and films made thereof | BAYER AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0376032-B1 | Stilbene dyes and films or sheets containing the same | BAYER AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| US-5340504-A | Water soluble polymer containing bis-, tris- or tetrakis-azo dyes | BAYER AG (DE) | 1994-08-23 | — | — | US | disclosed |
| US-5272259-A | Stilbene dyestuffs and light-polarizing films or sheets containing stilbene | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-21 | — | — | US | disclosed |
| EP-0498217-A1 | Dyes for polarising films and films made thereof | BAYER AG (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0376032-A2 | Stilbene dyes and films or sheets containing the same | BAYER AG (DE) | 1990-07-04 | — | — | EP | disclosed |