Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 known ✓ | Q9NR96 | 1/20 | 0.41 |
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.40 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.40 |
| ▸ | RAD1 | O60671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536243 | 0.99 | NT5E (0.56) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL29692725 | 0.99 | NT5E (0.56) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL1536241 | 0.99 | NT5E (0.56) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL6050413 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL2391190 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL7555155 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL30390242 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL2391199 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL6050520 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 | |
| SCHEMBL26114158 | 0.97 | NT5E (0.55) | NT5ERAD51MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752692-B1 | POLARIZER AND POLARIZING PLATE | NIPPON KAYAKU KK (JP) | 2017-10-18 | — | — | EP | disclosed |
| US-20140218628-A1 | Polarizer And Polarizing Plate | POLATECHNO CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| EP-2752692-A1 | POLARIZER AND POLARIZING PLATE | Nippon Kayaku Kabushiki Kaisha (JP) | 2014-07-09 | — | — | EP | disclosed |