SCHEMBL1399781

SCHEMBL1399781

O=[N+]([O-])c1ccc(C=Cc2ccc([N+](=O)[O-])cc2S(=O)(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 6/20 0.56
▸ PTGS1 P23219 2/20 0.56
▸ CYP19A1 P11511 2/20 0.53
▸ MEN1 O00255 2/20 0.52
▸ LMNA P02545 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ RAD51 Q06609 1/20 0.50
▸ NPC1 O15118 2/20 0.47
▸ MAPT P10636 2/20 0.47
▸ RAB9A P51151 2/20 0.47
▸ APP P05067 2/20 0.47
▸ FBP1 P09467 1/20 0.46
▸ TLR9 Q9NR96 1/20 0.46
▸ HTT P42858 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ NT5E P21589 1/20 0.44
▸ SNCA P37840 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9360466 1.00 PTGS2 (0.56) PTGS2PTGS1CYP19A1MEN1LMNA
SCHEMBL455776 0.92 RAD51 (0.56) PTGS2PTGS1MEN1LMNAKMT2A
SCHEMBL670637 0.92 RAD51 (0.56) PTGS2PTGS1MEN1LMNAKMT2A
SCHEMBL455775 0.92 RAD51 (0.56) PTGS2PTGS1MEN1LMNAKMT2A
SCHEMBL29356717 0.92 RAD51 (0.56) PTGS2PTGS1MEN1LMNAKMT2A
SCHEMBL8746878 0.92 PTGS2 (0.48) PTGS2PTGS1CYP19A1MEN1LMNA
SCHEMBL8746877 0.92 PTGS2 (0.48) PTGS2PTGS1CYP19A1MEN1LMNA
SCHEMBL8619058 0.92 NFE2L2 (0.55) PTGS2PTGS1CYP19A1MEN1LMNA
SCHEMBL8613119 0.92 NFE2L2 (0.55) PTGS2PTGS1CYP19A1MEN1LMNA
SCHEMBL9818822 0.91 RAD51 (0.58) PTGS2PTGS1MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021132-A Electrochemical process for preparing 4,4'-dinitrostilbene-2,2'-disulfonic acid and the salts thereof SANDOZ LTD. (CH) 1991-06-04 — — US claimed
EP-3474049-B1 POLARIZING MEMBER AND HEAD-UP DISPLAY DEVICE COMPRISING SAME POLATECHNO CO LTD (JP) 2023-11-15 — — EP disclosed
US-10585281-B2 Polarizing member and head-up display device comprising same POLATECHNO CO., LTD. (JP) 2020-03-10 — — US disclosed
US-20190293931-A1 POLARIZING MEMBER AND HEAD-UP DISPLAY DEVICE COMPRISING SAME POLATECHNO CO., LTD. (JP) 2019-09-26 — — US disclosed
US-20190204679-A1 LIQUID CRYSTAL DISPLAY DEVICE POLATECHNO CO., LTD. (JP) 2019-07-04 — — US disclosed
EP-2752693-B1 POLARIZING ELEMENT AND POLARIZING PLATE NIPPON KAYAKU KK (JP) 2019-05-15 — — EP disclosed
EP-3474049-A1 POLARIZING MEMBER AND HEAD-UP DISPLAY DEVICE COMPRISING SAME Polatechno Co., Ltd. (JP) 2019-04-24 — — EP disclosed
CN-109154691-A Polarizing member and head-up display with the polarizing member 日本宝来科技有限公司 2019-01-04 — — CN disclosed
US-20180321551-A1 LIQUID CRYSTAL DISPLAY DEVICE TOHOKU UNIVERSITY (JP) 2018-11-08 — — US disclosed
EP-3333615-A1 HEAD-UP DISPLAY DEVICE Polatechno Co., Ltd. (JP) 2018-06-13 — — EP disclosed
US-7931702-B2 Azo compound and salt thereof, and dye-containing polarizing film comprising the compound or salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-04-26 — — US disclosed
US-20110063546-A1 Azo Compound And Salt Thereof, And Dye-Containing Polarizing Film Comprising The Compound Or Salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-17 — — US disclosed
US-20110060134-A1 Azo Compound And Salt Thereof, And Dye-Containing Polarizing Film Comprising The Compound Or Salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-10 — — US disclosed
EP-2022828-B1 AZO COMPOUND AND SALT THEREOF, AND DYE-CONTAINING POLARIZING FILM COMPRISING THE COMPOUND OR SALT NIPPON KAYAKU KK (JP) 2011-03-02 — — EP disclosed
US-20090126127-A1 Azo compound and salt thereof, and dye-containing polarizing film comprising the compound or salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-05-21 — — US disclosed
EP-2022828-A1 AZO COMPOUND AND SALT THEREOF, AND DYE-CONTAINING POLARIZING FILM COMPRISING THE COMPOUND OR SALT Nippon Kayaku Kabushiki Kaisha (JP) 2009-02-11 — — EP disclosed
EP-0376032-B1 Stilbene dyes and films or sheets containing the same BAYER AG (DE) 1994-11-23 — — EP disclosed
US-5272259-A Stilbene dyestuffs and light-polarizing films or sheets containing stilbene BAYER AKTIENGESELLSCHAFT (DE) 1993-12-21 — — US disclosed
EP-0531569-A1 Manufacture of light-polarising films Agfa-Gevaert AG (DE) 1993-03-17 — — EP disclosed
EP-0376032-A2 Stilbene dyes and films or sheets containing the same BAYER AG (DE) 1990-07-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090126127-A1 Azo compound and salt thereof, and dye-containing polarizing film comprising the compound or salt REN, RCC1, NR3C2 PTGS2 4213/4885PTGS1 3278/4885CYP19A1 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback