SCHEMBL874690

SCHEMBL874690

CCCCCOS(=O)(=O)c1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.43
CA2 P00918 9/20 0.43
CA9 Q16790 8/20 0.43
CA12 O43570 3/20 0.42
CA7 P43166 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA3 P07451 2/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 2/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
TSHR P16473 3/20 0.41
RECQL P46063 2/20 0.41
MAPK1 P28482 2/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11779434 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL8744436 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL11238583 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL2417827 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL31371864 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL7545491 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL3140135 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL2230465 0.98 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL11423565 0.97 CA1 (0.43) CA1CA2CA9CA12CA7
SCHEMBL11697143 0.97 CA1 (0.43) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586599-B1 Formating carbon-carbon bonds between carbocyclic halogen and organosilicon compounds in the presence of coordination catalysts, nitrogen compounds and bases; efficiency; catalysis UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION 2003-07-01 US claimed
US-6403801-B1 MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, ARYLBORONIC ACID, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SELECTED FROM IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-06-11 US claimed
US-6403802-B1 MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, PRIMARY AND/OR SECONDARY AMINE, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SUCH AS IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-06-11 US claimed
US-6369265-B1 HETEROCOUPLING REACTION, MIXING IN A LIQUID AN ARYL HALIDE, BONDING TO AROMATIC RINGS, GRIGNARD REACTION, METAL COMPOUND AND HETEROCYCLIC CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-04-09 US claimed
US-6362357-B1 PHOSPHINE; USING ARYL HALIDES; ORGANOTIN COMPOUNDS UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-03-26 US claimed
WO-2001066248-A2 C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) 2001-09-13 WO claimed
US-5602228-A Nickel phosphate catalysts MAXDEM INCORPORATED (US) 1997-02-11 US claimed
WO-1996039455-A1 NICKEL PHOSPHITE CATALYSTS MAXDEM INCORPORATED (US) 1996-12-12 WO claimed
CN-109422674-B Organic molecules, in particular for optoelectronic devices 三星显示有限公司 2024-03-22 CN disclosed
US-20240075151-A1 CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS FISH & RICHARDSON PC 2024-03-07 US disclosed
US-20230406877-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KR) 2023-12-21 US disclosed
US-11807628-B2 Benzodiazepine derivatives and uses thereof INTOCELL, INC. (KR) 2023-11-07 US disclosed
US-11773219-B2 Functionalized polymers QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-03 US disclosed
US-20230285574-A1 CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS FISH & RICHARDSON PC 2023-09-14 US disclosed
EP-0985662-A2 Linker binding carriers for organic synthesis, their production and use Takeda Chemical Industries, Ltd. (JP) 2000-03-15 EP disclosed
US-5858907-A Nickel phosphite catalysts MAXDEM, INCORPORATED (US) 1999-01-12 US disclosed
CN-1201393-A Compositions and methods for treating bone deficiency disorders ZYMOGENETICS INC (US) 1998-12-09 CN disclosed
US-5602228-A Nickel phosphate catalysts MAXDEM INCORPORATED (US) 1997-02-11 US disclosed
WO-1996039455-A1 NICKEL PHOSPHITE CATALYSTS MAXDEM INCORPORATED (US) 1996-12-12 WO disclosed
US-4352788-A ARTERIES BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1982-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285574-A1 CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS CD44, EPCAM, ALG1 CA1 860/4885CA2 3633/4885CA9 1092/4885
US-11807628-B2 Benzodiazepine derivatives and uses thereof GABRB3, GABRB2, GABRB1 CA1 2795/4885CA2 3908/4885CA9 4784/4885
US-11773219-B2 Functionalized polymers PARG, PUF60, PCBP1 CA1 1988/4885CA2 4277/4885CA9 3071/4885
US-20230406877-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF VIP, ANTXR2, TNFRSF9 CA1 101/4885CA2 225/4885CA9 247/4885
US-20240075151-A1 CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS TNF, TNFRSF1A, TNFSF11 CA1 1032/4885CA2 4015/4885CA9 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.