SCHEMBL8746958

SCHEMBL8746958

CCCCC(CC)COC(=O)c1ccc(Cl)cc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.65
▸ MAPK1 P28482 3/20 0.65
▸ TSHR P16473 3/20 0.65
▸ CYP3A4 P08684 3/20 0.65
▸ CA2 P00918 1/20 0.65
▸ LMNA P02545 3/20 0.60
▸ PRSS1 P07477 1/20 0.59
▸ PRSS2 P07478 1/20 0.59
▸ PRSS3 P35030 1/20 0.59
▸ KMT2A Q03164 2/20 0.53
▸ HSD17B10 Q99714 1/20 0.52
▸ TDP1 Q9NUW8 4/20 0.47
▸ ATM Q13315 1/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226379 0.82 ALDH1A1 (0.77) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl) Phthalate SCHEMBL8769229 0.82 ALDH1A1 (0.86) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl) Phthalate SCHEMBL28246750 0.81 ALDH1A1 (0.97) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL10763925 0.80 ALDH1A1 (0.78) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl)Phthalate SCHEMBL29411299 0.79 ALDH1A1 (1.00) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl)Phthalate SCHEMBL21733281 0.79 ALDH1A1 (1.00) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL18069229 0.79 LMNA (0.74) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl) Phthalate SCHEMBL20271 0.79 ALDH1A1 (1.00) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl) Phthalate SCHEMBL29351619 0.79 ALDH1A1 (1.00) ALDH1A1MAPK1TSHRCYP3A4CA2
Bis(2-Ethylhexyl) Phthalate SCHEMBL2864306 0.79 ALDH1A1 (1.00) ALDH1A1MAPK1TSHRCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459349-B1 Silver halide color negative photosensitive material FUJI PHOTO FILM CO LTD (JP) 1997-03-26 — — EP disclosed
EP-0447969-B1 Yellow dye-forming coupler and silver halide color photographic material containing same FUJI PHOTO FILM CO LTD (JP) 1997-01-15 — — EP disclosed
EP-0432804-B1 Silver halide photographic photosensitive materials FUJI PHOTO FILM CO LTD (JP) 1996-07-03 — — EP disclosed
EP-0423764-B1 Silver halide colour photographic material and cyan coupler of the 2-phenylureido-5-acylaminophenol type FUJI PHOTO FILM CO LTD (JP) 1996-05-08 — — EP disclosed
US-5437965-A Storage stability, color sensitivity, reproduction quality FUJI PHOTO FILM CO., LTD. (JP) 1995-08-01 — — US disclosed
US-5427902-A Silver halide color photographic material containing acylacetamide yellow dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1995-06-27 — — US disclosed
US-5366856-A Cyan couplers, improved color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1994-11-22 — — US disclosed
US-5359080-A Acetylacetamide couplers; high sensitivity, color density, spectral absorption FUJI PHOTO FILM CO., LTD. (JP) 1994-10-25 — — US disclosed
US-5254446-A Pyrazoloazole magenta coupler; sharpness FUJI PHOTO FILM CO., LTD. (JP) 1993-10-19 — — US disclosed
US-5210011-A SILVER HALIDE PHOTOGRAPHIC PHOTOSENSITIVE MATERIAL CONTAINING TWO TYPES OF CYAN DYE FORMING COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1993-05-11 — — US disclosed
US-5206129-A Coupling reaction with oxidized species of primary aromatic amine derivative; improved color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1993-04-27 — — US disclosed
US-5112729-A Cyan coupler and an ultraviolet radiation absorber FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 — — US disclosed
US-5094938-A High coupling reactivity, high color density FUJI PHOTO FILM CO., LTD. (JP) 1992-03-10 — — US disclosed
CN-1057911-A Form the coupling agent of weld and the color silver halide photographic-material that contains this coupling agent FUJI PHOTO FILM CO LTD (JP) 1992-01-15 — — CN disclosed
EP-0447969-A1 Yellow dye-forming coupler and silver halide color photographic material containing same FUJI PHOTO FILM CO., LTD. (JP) 1991-09-25 — — EP disclosed
EP-0432804-A2 Silver halide photographic photosensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 — — EP disclosed
EP-0423764-A2 Silver halide colour photographic material and cyan coupler of the 2-phenylureido-5-acylaminophenol type FUJI PHOTO FILM CO., LTD. (JP) 1991-04-24 — — EP disclosed
EP-0246616-A2 Silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1987-11-25 — — EP disclosed
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