SCHEMBL8747358

SCHEMBL8747358

CCCC(O)C(F)CC(C)OC(=O)c1[c]cccc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.33
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CTSK P43235 2/20 0.30
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSH P09668 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747453 0.87 PRKCA (0.36) KDM4ECTSKCTSLCTSB
SCHEMBL8747402 0.86 TSHR (0.35) ALDH1A1POLBTSHRKMT2A
SCHEMBL8747359 0.80 TSHR (0.36) ALDH1A1POLBTSHRMEN1KMT2A
SCHEMBL8747427 0.80 ALDH1A1 (0.40) ALDH1A1KDM4EPOLBTSHRMEN1
SCHEMBL8747429 0.80 ALDH1A1 (0.40) ALDH1A1KDM4EPOLBTSHRMEN1
SCHEMBL6953946 0.78 MAPT (0.41) ALDH1A1KDM4EPOLBTSHRMEN1
SCHEMBL11469429 0.75 PRKCA (0.48) ALDH1A1KDM4EPOLBMEN1KMT2A
SCHEMBL8747451 0.75 GABRA1 (0.30)
SCHEMBL10700173 0.75 TSHR (0.37) ALDH1A1POLBTSHRKMT2A
SCHEMBL8747437 0.73 PRKCA (0.40) ALDH1A1KDM4EPOLBTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585032-B1 Anti-ferroelectric liquid crystal and liquid crystal display device MITSUBISHI GAS CHEMICAL CO (JP) 1997-03-05 EP disclosed
US-5340498-A High speed response MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-08-23 US disclosed
EP-0585032-A1 Anti-ferroelectric liquid crystal and liquid crystal display device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-03-02 EP disclosed