SCHEMBL8747418

SCHEMBL8747418

CC(C)(c1ccc(OC(=O)N2CC2)cc1)c1ccc(OC(=O)N2CC2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
NPC1 O15118 2/20 0.69
MAPT P10636 1/20 0.69
HTT P42858 1/20 0.69
ALDH1A1 P00352 1/20 0.59
POLB P06746 1/20 0.59
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
TRPV1 Q8NER1 3/20 0.52
TRPA1 O75762 1/20 0.52
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GAA P10253 1/20 0.49
NPY2R P49146 1/20 0.48
SRD5A1 P18405 2/20 0.47
LIPE Q05469 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31717669 0.93 SMN1; SMN2 (0.74) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL6581443 0.92 MAPT (0.60) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL31717900 0.92 SMN1; SMN2 (0.82) RAB9ASMN1; SMN2NPC1MAPTHTT
Hydrochloric Acid SCHEMBL6581546 0.91 MAPT (0.58) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL31717524 0.89 RAB9A (0.83) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL31717301 0.88 SMN1; SMN2 (0.67) RAB9ASMN1; SMN2NPC1MAPTHTT
Hydrochloric Acid SCHEMBL6579257 0.88 SMN1; SMN2 (0.58) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL31717596 0.88 SMN1; SMN2 (0.71) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL3092281 0.86 SMN1; SMN2 (0.74) RAB9ASMN1; SMN2NPC1MAPTHTT
SCHEMBL8747161 0.84 ALDH1A1 (0.79) RAB9ASMN1; SMN2NPC1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP claimed
EP-0512560-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-20 EP claimed
EP-0526072-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-09-13 EP claimed
EP-0514807-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-08-23 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5384303-A Heat sensitive elements for color images with stabilizers NEW OJI PAPER CO., LTD. (JP) 1995-01-24 US claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5312796-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-17 US claimed
US-5292711-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-03-08 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535788-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
EP-0526072-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-02-03 EP claimed
EP-0514807-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-25 EP claimed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP claimed
EP-0503856-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1992-09-16 EP claimed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP disclosed
EP-0514807-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-25 EP disclosed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP disclosed
EP-0503856-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1992-09-16 EP disclosed