Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837744 | 0.83 | DPP4 (0.41) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL13158249 | 0.80 | L3MBTL1 (0.50) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL27814580 | 0.79 | SMN1; SMN2 (0.59) | KMT2AALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL17965782 | 0.78 | SRC (0.50) | L3MBTL1ATMKMT2AALDH1A1AAK1 | |
| SCHEMBL7043298 | 0.78 | L3MBTL1 (0.55) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL18206839 | 0.78 | ALDH1A1 (0.58) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL18206841 | 0.78 | ALDH1A1 (0.58) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL27970498 | 0.77 | ATM (0.44) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL27365551 | 0.77 | KMT2A (0.47) | L3MBTL1ATMKMT2AALDH1A1CYP3A4 | |
| SCHEMBL8593879 | 0.77 | LMNA (0.52) | L3MBTL1ATMKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641305-B1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEM CO (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5359125-A | Using 2,2'-bisacetoacetate as crosslinking agent | EASTMAN CHEMICAL COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5254637-A | Curable enamel with 2,2*-bisacetoacetate crosslinking agents | EASTMAN KODAK COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| US-5247122-A | 2,2'-bisacetoacetates useful as crosslinking agents | EASTMAN KODAK COMPANY (US) | 1993-09-21 | — | — | US | disclosed |