SCHEMBL8747632

SCHEMBL8747632

Nc1cc(S(=O)(=O)O)c(O)c(S(=O)(=O)O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
TDP1 Q9NUW8 4/20 0.68
HSD17B10 Q99714 4/20 0.68
CASP1 P29466 1/20 0.68
CASP7 P55210 1/20 0.68
NQO1 P15559 1/20 0.44
RAPGEF4 Q8WZA2 1/20 0.44
CASP6 P55212 4/20 0.42
GAA P10253 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
NSD2 O96028 3/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 2/20 0.42
RECQL P46063 2/20 0.42
APEX1 P27695 1/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
NT5E P21589 4/20 0.41
TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10881182 0.91 ALDH1A1 (0.63) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL15449420 0.85 ALDH1A1 (0.58) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL17774556 0.85 THRB (0.58) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL1270607 0.82 ALDH1A1 (0.53) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL15309546 0.82 ALDH1A1 (0.54) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL342398 0.82 TDP1 (1.00) ALDH1A1TDP1HSD17B10CASP1CASP7
Ammonia Solution, Strong SCHEMBL11775754 0.80 TDP1 (0.96) ALDH1A1TDP1HSD17B10CASP1CASP7
Ammonia Solution, Strong SCHEMBL11775759 0.80 TDP1 (0.96) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL15449405 0.80 TDP1 (0.72) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL4649650 0.80 ALDH1A1 (0.52) ALDH1A1TDP1HSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553890-B2 Aqueous redox flow batteries UCHICAGO ARGONNE, LLC (US) 2020-02-04 US disclosed
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed