SCHEMBL8747637

SCHEMBL8747637

O=C(Cl)CCc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
LMNA P02545 4/20 0.43
ALDH1A1 P00352 9/20 0.42
TSHR P16473 2/20 0.42
GAA P10253 2/20 0.42
NT5E P21589 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
PRMT1 Q99873 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9135914 0.83 FFAR1 (0.50) CA1CA2LMNAALDH1A1TSHR
SCHEMBL9845455 0.82 CA1 (0.70) CA1CA2LMNAALDH1A1TSHR
SCHEMBL11583429 0.81 LMNA (0.56) CA1CA2LMNAALDH1A1TSHR
SCHEMBL30849591 0.81 ALDH1A1 (0.57) CA1CA2LMNAALDH1A1TSHR
SCHEMBL8507036 0.80 LMNA (0.46) CA1CA2LMNAALDH1A1TSHR
SCHEMBL17212140 0.78 LMNA (0.48) CA1CA2LMNAALDH1A1TSHR
SCHEMBL30446884 0.77 CA2 (0.57) CA1CA2LMNAALDH1A1TSHR
SCHEMBL9551303 0.77 CA2 (0.44) CA1CA2LMNAALDH1A1TSHR
SCHEMBL11082491 0.77 IAPP (0.54) CA1CA2LMNAALDH1A1TSHR
SCHEMBL28002327 0.76 ALDH1A1 (0.51) CA1CA2LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed