SCHEMBL8747671

SCHEMBL8747671

C=CC(=O)OCN1C(=O)C=CC1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HIF1A Q16665 4/20 0.53
HPGD P15428 3/20 0.53
BLM P54132 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
WRN Q14191 1/20 0.53
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
TSHR P16473 6/20 0.42
TP53 P04637 4/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 1/20 0.40
MAPK1 P28482 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MGLL Q99685 5/20 0.37
FAAH O00519 3/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030571 0.83 MGLL (0.50) ALDH1A1HIF1AHPGDBLMCYP1A2
SCHEMBL15483460 0.80 TSHR (0.53) ALDH1A1HIF1AHPGDBLMCYP1A2
SCHEMBL14591387 0.80 GSK3A (0.57) ALDH1A1HIF1AHPGDBLMCYP1A2
SCHEMBL13893299 0.79 TSHR (0.56) ALDH1A1HIF1AHPGDTSHRTP53
SCHEMBL14591385 0.79 GSK3A (0.56) ALDH1A1HIF1AHPGDBLMCYP1A2
SCHEMBL28034447 0.77 ALDH1A1 (0.55) ALDH1A1HIF1AHPGDBLMCYP1A2
SCHEMBL19334645 0.77 PIN1 (0.47) ALDH1A1HIF1ATSHRTP53CYP3A4
SCHEMBL5900157 0.77 NPSR1 (0.55) ALDH1A1HPGDCYP1A2CYP2C19TSHR
SCHEMBL10759118 0.76 ALDH1A1 (0.63) ALDH1A1HIF1AHPGDBLMCYP1A2
SCHEMBL786236 0.75 TSHR (0.45) ALDH1A1HIF1AHPGDTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111142283-A Light control film and vehicle body panel including the same 丰田纺织株式会社 2020-05-12 CN disclosed
CN-103586456-B A kind of High-dispersity silver powder and preparation method thereof and application GUANGZHOU CHEMISTRY CO., LTD. CHINESE ACADEMY OF SCIENCES (CN) 2016-01-20 CN disclosed
EP-0464609-B1 Photographic element FUJI PHOTO FILM CO LTD (JP) 1997-03-12 EP disclosed
US-5212051-A Acrylic copolymers containing carboxy, sulfo or phosphate groups modified by cellulose ethers or esters; barriers to diffusion for diffusion transfer films; flexible coatings FUJI PHOTO FILM CO., LTD. (JP) 1993-05-18 US disclosed
EP-0464609-A2 Photographic element FUJI PHOTO FILM CO., LTD. (JP) 1992-01-08 EP disclosed