SCHEMBL8747783

SCHEMBL8747783

O=C(Br)CCc1cc(C2CCCCC2)c(O)c(C2CCCCC2)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
NUDT1 P36639 1/20 0.43
BACE1 P56817 1/20 0.43
THRB P10828 3/20 0.40
THRA P10827 2/20 0.40
PTGDR2 Q9Y5Y4 8/20 0.36
PTGDR Q13258 3/20 0.36
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33
PTGER2 P43116 1/20 0.33
CCR5 P51681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38822 0.86 THRB (0.50) MEN1KMT2AKDM4EMAPTNUDT1
Ammonia Solution, Strong SCHEMBL4052129 0.84 THRB (0.49) MEN1KMT2AKDM4EMAPTNUDT1
Ethylene SCHEMBL4047965 0.83 THRB (0.48) MEN1KMT2AKDM4EMAPTNUDT1
SCHEMBL4045061 0.83 ALOX5 (0.46) MEN1KMT2AKDM4EMAPTNUDT1
SCHEMBL4050039 0.82 PTGDR2 (0.46) MEN1KMT2AKDM4EMAPTNUDT1
SCHEMBL10352291 0.82 NUDT1 (0.44) MEN1KMT2AKDM4EMAPTNUDT1
Alcohol SCHEMBL28852088 0.81 THRB (0.46) MEN1KMT2AKDM4EMAPTNUDT1
Ethylene SCHEMBL4042411 0.81 ALOX5 (0.44) MEN1KMT2AKDM4EMAPTNUDT1
SCHEMBL4594694 0.80 NUDT1 (0.47) MEN1KMT2AKDM4EMAPTNUDT1
SCHEMBL9182472 0.80 NUDT1 (0.50) MEN1KMT2AKDM4EMAPTNUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed