Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488004 | 0.88 | HTT (0.45) | GABRG2GABRB3GABRA5ALDH1A1HTT | |
| SCHEMBL8490660 | 0.87 | TP53 (0.36) | TP53TARBP2GABRG2GABRB3GABRA5 | |
| SCHEMBL7581819 | 0.86 | MAPT (0.36) | TP53TARBP2GABRG2GABRB3GABRA5 | |
| SCHEMBL8492575 | 0.86 | ALDH1A1 (0.39) | TP53GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL8817056 | 0.86 | MLYCD (0.41) | TP53ALDH1A1HTTMAPTLMNA | |
| SCHEMBL7573179 | 0.86 | HSP90AA1 (0.34) | TP53TARBP2GABRG2GABRB3GABRA5 | |
| SCHEMBL7572967 | 0.86 | ALDH1A1 (0.34) | TP53TARBP2GABRG2GABRB3GABRA5 | |
| SCHEMBL8490493 | 0.85 | ALDH1A1 (0.36) | TP53ALDH1A1HTTMAPTHSP90AA1 | |
| SCHEMBL8747816 | 0.85 | ELANE (0.42) | TP53ALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL8816925 | 0.84 | ALDH1A1 (0.35) | TP53TARBP2GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |
| WO-1997023491-A1 | NEW HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-03 | — | — | WO | disclosed |