Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748098 | 0.88 | ALDH1A1 (0.34) | ALDH1A1TRPM8NPC1LMNAMAPT | |
| SCHEMBL9247502 | 0.88 | PPARA (0.36) | — | |
| SCHEMBL8747895 | 0.79 | SLC16A3 (0.43) | — | |
| Hydrochloric Acid SCHEMBL9244003 | 0.78 | SLC16A3 (0.42) | — | |
| SCHEMBL9244843 | 0.78 | SLC16A3 (0.37) | — | |
| SCHEMBL9243997 | 0.78 | SLC16A3 (0.35) | ALDH1A1 | |
| SCHEMBL9246981 | 0.76 | PPARA (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL9247301 | 0.74 | ADORA3 (0.43) | — | |
| SCHEMBL9251152 | 0.72 | SLC16A3 (0.41) | — | |
| SCHEMBL9248163 | 0.72 | SLC16A3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |