Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874082 | 0.91 | MAPT (0.38) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL873584 | 0.90 | KMT2A (0.40) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL874570 | 0.90 | MOK (0.43) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL874210 | 0.89 | MAPT (0.40) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL874291 | 0.88 | CHRNA7 (0.39) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL875385 | 0.88 | MAPT (0.40) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL874686 | 0.86 | CYP3A4 (0.42) | NAMPTCHRNA7DRD2DRD3JAK2 | |
| SCHEMBL874151 | 0.83 | CYP3A4 (0.40) | MAPTKDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL874083 | 0.83 | KDM4E (0.38) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL874025 | 0.82 | NAMPT (0.41) | KMT2AMAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |