Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874837 | 0.88 | KMT2A (0.37) | CHRNA7BCHEACHENAMPTKMT2A | |
| SCHEMBL873877 | 0.88 | CHRNA7 (0.42) | CHRNA7BCHEACHENAMPTSYK | |
| SCHEMBL873584 | 0.88 | KMT2A (0.40) | NAMPTKMT2ASYKATMRXFP1 | |
| SCHEMBL873721 | 0.87 | BCHE (0.39) | CHRNA7BCHEACHENAMPTFLT3 | |
| SCHEMBL875500 | 0.86 | ATR (0.41) | CHRNA7NAMPTSYKDRD2DRD3 | |
| SCHEMBL882629 | 0.85 | CHRNA7 (0.42) | CHRNA7NAMPTKMT2ASYKATM | |
| SCHEMBL873722 | 0.80 | RXFP1 (0.38) | CHRNA7NAMPTSYKATMRXFP1 | |
| SCHEMBL874082 | 0.80 | MAPT (0.38) | CHRNA7NAMPTKMT2AATMDRD2 | |
| SCHEMBL874515 | 0.79 | ATR (0.43) | CHRNA7NAMPTDRD2DRD3 | |
| SCHEMBL875501 | 0.79 | CHRNA7 (0.40) | CHRNA7DYRK1ABCHEACHENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |