Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874837 | 0.90 | KMT2A (0.37) | KMT2AMAPTRAB9AATMRXFP1 | |
| SCHEMBL874835 | 0.88 | MEN1 (0.43) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL874291 | 0.88 | CHRNA7 (0.39) | KMT2AMAPTRAB9AATMRXFP1 | |
| SCHEMBL873820 | 0.85 | ATR (0.46) | KMT2AMEN1NPSR1NAMPTJAK2 | |
| SCHEMBL874280 | 0.85 | BCHE (0.39) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL874082 | 0.81 | MAPT (0.38) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL874570 | 0.79 | MOK (0.43) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL874515 | 0.79 | ATR (0.43) | NPSR1NAMPTJAK2 | |
| SCHEMBL874210 | 0.78 | MAPT (0.40) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL874281 | 0.78 | RAB9A (0.40) | KMT2AMEN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |