Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227751 | 0.90 | SLC6A2 (0.47) | HTR2CSLC6A2SLC6A4KDM4EMEN1 | |
| SCHEMBL31525035 | 0.87 | HSD17B10 (0.47) | KDM4EMEN1GAAMAPTHTT | |
| SCHEMBL3253975 | 0.87 | HSD17B10 (0.47) | KDM4EMEN1GAAMAPTHTT | |
| SCHEMBL1065970 | 0.84 | MEN1 (0.47) | KDM4EMEN1GAAMAPTHTT | |
| SCHEMBL28316412 | 0.84 | ALDH1A1 (0.47) | KDM4EMEN1GAAMAPTHTT | |
| SCHEMBL7335158 | 0.82 | HSP90AA1 (0.49) | KDM4EMEN1GAAMAPTHTT | |
| SCHEMBL3536567 | 0.81 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL2205192 | 0.81 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL8560822 | 0.78 | MEN1 (0.43) | HTR2CMEN1GAAMAPTHTT | |
| Piperazine SCHEMBL27288925 | 0.77 | HSD17B10 (0.52) | HTR2CMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1322196-A | Naphthalenecarboxamides as tachykinin receptor antagonists | ASTRA ZENECA N N (SE) | 2001-11-14 | — | — | CN | disclosed |
| CN-1059668-C | Process for preparing N-aliphatic substituted P-phenylenediamines | MONSANTO CO (US) | 2000-12-20 | — | — | CN | disclosed |
| EP-0641308-B1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES | MONSANTO CO (US) | 1997-03-12 | — | — | EP | disclosed |
| EP-0641308-A1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES. | MONSANTO CO (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993024443-A1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5252737-A | Process for preparing N-aliphatic substituted p-phenylenediamines | MONSANTO COMPANY (US) | 1993-10-12 | — | — | US | disclosed |