Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GALK1 | P51570 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495381 | 0.97 | — | — | |
| Fluoride Ion SCHEMBL12474470 | 0.95 | KMT2A (0.38) | KMT2AMEN1PABPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL6267344 | 0.95 | KMT2A (0.38) | KMT2AMEN1PABPC1RAB9ATSHR | |
| Bromide SCHEMBL28737975 | 0.95 | KMT2A (0.38) | KMT2AMEN1PABPC1RAB9ATSHR | |
| Bromide SCHEMBL30517303 | 0.95 | KMT2A (0.38) | KMT2AMEN1PABPC1RAB9ATSHR | |
| SCHEMBL1787783 | 0.88 | ACHE (0.37) | KMT2AMEN1PABPC1RAB9ATSHR | |
| Perchlorate SCHEMBL9052014 | 0.86 | KDM4E (0.34) | KMT2AMEN1PABPC1RAB9ATSHR | |
| SCHEMBL11598710 | 0.83 | CCR1 (0.41) | KMT2AMEN1PABPC1RAB9ATSHR | |
| Hexadecane SCHEMBL25192618 | 0.81 | HTT (0.41) | KMT2AMEN1RAB9ATSHRACHE | |
| Sulfuric Acid SCHEMBL5598595 | 0.81 | USP2 (0.35) | KMT2AMEN1PABPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494572-A | SOLVENT EXTRACTION WITH PYRIDINIUM SALT | GENERAL SEKIYU KABUSHIKIKAISHA (JP) | 1996-02-27 | — | — | US | claimed |
| JP-5202367-A | — | — | None | — | — | JP | disclosed |
| EP-0653477-B1 | Use of an organic solvent for denitrogenationation of light oil by extraction | GEN SEKIYU KABUSHIKI KAISHA (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0538738-B1 | Desulfurization and Decolourizing of light oil by extraction | GEN SEKIYU KABUSHIKI KAISHA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5494572-A | SOLVENT EXTRACTION WITH PYRIDINIUM SALT | GENERAL SEKIYU KABUSHIKIKAISHA (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0653477-A2 | Desulfurization and denitration of light oil by extraction | GENERAL SEKIYU KABUSHIKI KAISHA (JP) | 1995-05-17 | — | — | EP | disclosed |
| JP-H05202367-A | METHOD FOR DESULFURIZING AND DENITRATING LIGHT OIL BY EXTRACTION | GENERAL SEKIYU KK | 1993-08-10 | — | — | JP | disclosed |
| EP-0538738-A2 | Desulfurization and Decolourizing of light oil by extraction | GENERAL SEKIYU KABUSHIKI KAISHA (JP) | 1993-04-28 | — | — | EP | disclosed |