Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Perchlorate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GALK1 | P51570 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL9052017 | 0.94 | RAB9A (0.35) | KDM4EKMT2ANSD2POLBMAPT | |
| SCHEMBL2495381 | 0.89 | — | — | |
| Bromide SCHEMBL30517303 | 0.86 | KMT2A (0.38) | KDM4EKMT2ANSD2POLBMAPT | |
| Hydrochloric Acid SCHEMBL6267344 | 0.86 | KMT2A (0.38) | KDM4EKMT2ANSD2POLBMAPT | |
| Fluoride Ion SCHEMBL12474470 | 0.86 | KMT2A (0.38) | KDM4EKMT2ANSD2POLBMAPT | |
| Bromide SCHEMBL28737975 | 0.86 | KMT2A (0.38) | KDM4EKMT2ANSD2POLBMAPT | |
| Bromide SCHEMBL8748601 | 0.86 | KMT2A (0.38) | KDM4EKMT2ANSD2POLBMAPT | |
| Sulfuric Acid SCHEMBL5598588 | 0.81 | KDM4E (0.33) | KDM4EKMT2ANSD2POLBMAPT | |
| SCHEMBL1787783 | 0.80 | ACHE (0.37) | KDM4EKMT2ANSD2POLBMAPT | |
| Iodide SCHEMBL9052632 | 0.78 | RAB9A (0.38) | KDM4EKMT2ANSD2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006102-A1 | PROCESS FOR THE PREPARATION OF OLIGOSACCHARIDE MIXTURES | CIBA-GEIGY AG (CH) | 1996-02-29 | — | — | WO | disclosed |