Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.40 |
| ▸ | RARG | P13631 | 12/20 | 0.40 |
| ▸ | RXRA | P19793 | 10/20 | 0.40 |
| ▸ | RARA | P10276 | 10/20 | 0.40 |
| ▸ | RXRB | P28702 | 8/20 | 0.40 |
| ▸ | RXRG | P48443 | 6/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108628 | 0.94 | RARB (0.36) | RARBRARGRXRARARARXRB | |
| SCHEMBL8748829 | 0.82 | RARB (0.55) | RARBRARGRXRARARARXRB | |
| SCHEMBL8748608 | 0.80 | RXRA (0.46) | RARBRARGRXRARARARXRB | |
| SCHEMBL8106743 | 0.79 | MEN1 (0.42) | RARBRARGRXRARARARXRB | |
| SCHEMBL8093109 | 0.79 | RARG (0.43) | RARBRARGRXRARARARXRB | |
| SCHEMBL8757257 | 0.79 | RARB (0.40) | RARBRARGRXRARARARXRB | |
| SCHEMBL8100983 | 0.78 | RARB (0.44) | RARBRARGRXRARARARXRB | |
| SCHEMBL8102431 | 0.77 | RARB (0.43) | RARBRARGRXRARARARXRB | |
| SCHEMBL8106311 | 0.77 | RARB (0.37) | RARBRARGRXRARARARXRB | |
| SCHEMBL8093042 | 0.76 | RORC (0.45) | RARBRARGRXRARARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661260-B1 | New bi-aromatic compounds derived from amides pharmaceutical compositions and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1997-03-12 | — | — | EP | disclosed |
| EP-0661260-A1 | New bi-aromatic compounds derived from amides pharmaceutical compositions and cosmetic compositions containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-07-05 | — | — | EP | disclosed |