Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17443310 | 0.85 | GAA (0.60) | KMT2AGAAALDH1A1LMNAMAPT | |
| SCHEMBL17550644 | 0.84 | POLB (0.60) | KMT2APKMGAAHSD11B1ALDH1A1 | |
| SCHEMBL2775897 | 0.83 | KMT2A (0.59) | KMT2APKMGAAALDH1A1LMNA | |
| SCHEMBL2178479 | 0.82 | KMT2A (0.78) | KMT2APKMGAAHSD11B1ALDH1A1 | |
| SCHEMBL3152558 | 0.81 | KMT2A (0.62) | KMT2APKMGAAALDH1A1LMNA | |
| SCHEMBL19346040 | 0.81 | LMNA (0.60) | KMT2APKMALDH1A1LMNAMAPT | |
| SCHEMBL18503840 | 0.81 | KMT2A (1.00) | KMT2AGAAHSD11B1ALDH1A1MAPT | |
| SCHEMBL23703133 | 0.80 | KMT2A (0.73) | KMT2APKMGAAHSD11B1ALDH1A1 | |
| SCHEMBL1939652 | 0.80 | KMT2A (0.73) | KMT2AGAAHSD11B1ALDH1A1LMNA | |
| SCHEMBL1464359 | 0.80 | KMT2A (0.73) | KMT2AGAAHSD11B1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916966-A | STRAD binding agents and uses thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| CN-103228634-A | Matrix metalloproteinase inhibitors | RANBAXY LAB LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-103221386-A | Matrix metalloproteinase inhibitors | RANBAXY LAB LTD | 2013-07-24 | — | — | CN | disclosed |
| EP-0087446-B1 | METHOD OF FORMING A PHOTOGRAPHIC DYE IMAGE | KODAK LIMITED (GB) | 1986-07-09 | — | — | EP | disclosed |
| US-4481268-A | METALLIZED AZO OR AZO-METHINE DYES | EASTMAN KODAK COMPANY (US) | 1984-11-06 | — | — | US | disclosed |
| EP-0087446-A1 | METHOD OF FORMING A PHOTOGRAPHIC DYE IMAGE. | KODAK LTD (GB) | 1983-09-07 | — | — | EP | disclosed |
| WO-1983000939-A1 | METHOD OF FORMING A PHOTOGRAPHIC DYE IMAGE | BAILEY, JOSEPH | 1983-03-17 | — | — | WO | disclosed |