Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | PHGDH | O43175 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412217 | 0.93 | KMT2A (0.64) | KMT2AGAANPC1ALDH1A1KDM4E | |
| SCHEMBL2443525 | 0.88 | KMT2A (0.57) | KMT2AGAANPC1ALDH1A1KDM4E | |
| SCHEMBL7413641 | 0.87 | KMT2A (0.60) | KMT2AGAANPC1ALDH1A1POLB | |
| SCHEMBL2178479 | 0.86 | KMT2A (0.78) | KMT2AGAAALDH1A1HSD11B1NPSR1 | |
| SCHEMBL18503840 | 0.85 | KMT2A (1.00) | KMT2AGAAALDH1A1POLBHSD11B1 | |
| SCHEMBL12102109 | 0.84 | KMT2A (0.53) | KMT2AGAANPC1ALDH1A1POLB | |
| SCHEMBL7870795 | 0.84 | ALDH1A1 (0.71) | KMT2AGAAALDH1A1KDM4EPOLB | |
| SCHEMBL23703133 | 0.83 | KMT2A (0.73) | KMT2AGAAALDH1A1KDM4EPOLB | |
| SCHEMBL1939652 | 0.83 | KMT2A (0.73) | KMT2AGAAALDH1A1POLBHSD11B1 | |
| SCHEMBL11230795 | 0.83 | KMT2A (0.73) | KMT2AGAAALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | SOOCHOW UNIVERSITY (CN) | 2023-02-23 | — | — | US | disclosed |
| CN-108117528-B | 2, 5-substituent-1, 3, 4-oxadiazole sulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-108191786-B | 2, 5-substituent-1, 3, 4-oxadiazole disulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | disclosed |
| US-8299111-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-30 | — | — | US | disclosed |
| US-8299111-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-30 | — | — | US | disclosed |
| US-8299111-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-30 | — | — | US | disclosed |
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |
| US-7935715-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-05-03 | — | — | US | disclosed |
| US-7935715-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-05-03 | — | — | US | disclosed |
| US-7935715-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-05-03 | — | — | US | disclosed |
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |
| CN-101007794-A | N,N'-disubstituted piperazine derivative, and its preparation method and medicinal composition and uses | SHANGHAI INST MATERIA MEDICA (CN) | 2007-08-01 | — | — | CN | disclosed |
| US-4892922-A | Polyester polymer containing the residue of a benzopyran colorant compound and shaped articles produced therefrom | EASTMAN KODAK COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4705737-A | Heat developable photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0120403-B1 | HEAT DEVELOPABLE COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |
| EP-0120403-A2 | Heat developable color photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4326066-A | Triazolyl coumarin compounds, processes for their preparation and their use as whiteners and laser dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | KMT2A 3627/4885GAA 4570/4885NPC1 1183/4885 |
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | TST, CBS, STS | KMT2A 2093/4885GAA 707/4885NPC1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.