Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882696 | 0.91 | CYP1A2 (0.47) | MGLLNOTUMKMT2AMEN1GAA | |
| SCHEMBL875189 | 0.82 | POLB (0.58) | KMT2AMEN1SMN1; SMN2CYP2C9 | |
| SCHEMBL882700 | 0.74 | POLB (0.60) | KMT2AMEN1 | |
| SCHEMBL874365 | 0.73 | GAA (0.47) | GAAMAPTRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL875939 | 0.73 | POLB (0.56) | KMT2AMEN1 | |
| SCHEMBL3828117 | 0.71 | CYP1A2 (0.53) | KMT2AMEN1MAPTRAB9AMAPK1 | |
| SCHEMBL874463 | 0.69 | RAB9A (0.65) | KMT2AMEN1GAAMAPTRAB9A | |
| SCHEMBL3831660 | 0.68 | CYP1A2 (0.53) | KMT2AMEN1GAAMAPTRAB9A | |
| SCHEMBL5734672 | 0.66 | CYP1A2 (0.56) | KMT2AMEN1MAPTSMN1; SMN2CYP1A2 | |
| Propionic Acid SCHEMBL28285873 | 0.66 | RAB9A (0.51) | NOTUMKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |