Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CDC7 | O00311 | 4/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883107 | 0.88 | TRPM8 (0.49) | GAAKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL874463 | 0.82 | RAB9A (0.65) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL14018508 | 0.77 | RAB9A (0.77) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL15049277 | 0.76 | GAA (0.58) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL27997095 | 0.75 | GAA (0.43) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL28245733 | 0.74 | GAA (0.46) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL10069158 | 0.74 | CD274 (0.41) | NPC1ALDH1A1HPGDMAPTPPARA | |
| SCHEMBL28245757 | 0.74 | RAB9A (0.56) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL15049103 | 0.74 | RAB9A (0.62) | GAARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL874883 | 0.73 | MGLL (0.50) | GAARAB9AMAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |