Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.57 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140684 | 0.84 | KMT2A (0.41) | CES1CES2FNTAFNTBMEN1 | |
| SCHEMBL10562353 | 0.84 | CES1 (0.55) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL10562346 | 0.84 | CES1 (0.55) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL9404036 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AHDAC8HDAC6MAPK1 | |
| SCHEMBL9404025 | 0.80 | KDM4E (0.37) | CES1CES2FNTAFNTBALDH1A1 | |
| SCHEMBL28366287 | 0.80 | CES2 (0.47) | CES1CES2FNTAFNTBALDH1A1 | |
| SCHEMBL106635 | 0.80 | CES1 (0.73) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL8749069 | 0.79 | CES1 (0.48) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL29523177 | 0.78 | CES1 (0.70) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL9404039 | 0.77 | MAPT (0.56) | CES1ALDH1A1HDAC8HDAC6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148363-B2 | Heterocyclic compounds as factor IXA inhibitors | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
| US-5627006-A | ALKENYLOXY-SUBSTITUTED POLYVINYLPHENOLS, PHOTOSENSITIVE ACID GENERATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0552548-B1 | Resist material | WAKO PURE CHEM IND LTD (JP) | 1997-03-19 | — | — | EP | disclosed |
| EP-0323050-B1 | Photosensitive compound | WAKO PURE CHEM IND LTD (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5250669-A | Thermostability, photoresists | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0552548-A1 | Resist material | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0323050-A2 | Photosensitive compound | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0319325-A2 | Photosensitive material and process for forming pattern using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | F9, F12, F8 | CES1 264/4885CES2 1763/4885FNTA 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.