SCHEMBL8749094

SCHEMBL8749094

CCCCCCCCC(=O)OC(=O)[C@@H](N)CCC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.47
MAPT P10636 2/20 0.45
LMNA P02545 4/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
SOAT1 P35610 2/20 0.45
FAAH O00519 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALDH1A1 P00352 1/20 0.44
PAM P19021 2/20 0.44
KDM4E B2RXH2 2/20 0.43
DUSP3 P51452 1/20 0.43
MAPK1 P28482 1/20 0.42
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5548781 1.00 DGKA (0.47) DGKAMAPTLMNAKMT2AMEN1
SCHEMBL6940812 1.00 DGKA (0.47) DGKAMAPTLMNAKMT2AMEN1
SCHEMBL30197361 1.00 DGKA (0.47) DGKAMAPTLMNAKMT2AMEN1
SCHEMBL29431880 0.98 DGKA (0.46) DGKAMAPTLMNAKMT2AMEN1
SCHEMBL29031163 0.98 DGKA (0.46) DGKAMAPTLMNAKMT2AMEN1
SCHEMBL9665984 0.98 DGKA (0.44) DGKAMAPTLMNAKMT2AMEN1
Octadecanoic Acid Amide SCHEMBL4644915 0.93 PAM (0.47) DGKAKMT2AMEN1ALDH1A1PAM
Glutamine SCHEMBL18408962 0.91 KMT2A (0.49) MAPTKMT2ACYP1A2PAMALOX15
SCHEMBL346381 0.90 DGKA (0.50) DGKAMAPTLMNAKMT2AMEN1
SCHEMBL336371 0.90 DGKA (0.50) DGKAMAPTLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0571198-A1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1993-11-24 EP disclosed