Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749094 | 1.00 | DGKA (0.47) | DGKAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL6940812 | 1.00 | DGKA (0.47) | DGKAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL30197361 | 1.00 | DGKA (0.47) | DGKAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL29431880 | 0.98 | DGKA (0.46) | DGKAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL29031163 | 0.98 | DGKA (0.46) | DGKAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL9665984 | 0.98 | DGKA (0.44) | DGKAMAPTLMNAKMT2AMEN1 | |
| Octadecanoic Acid Amide SCHEMBL4644915 | 0.93 | PAM (0.47) | DGKAKMT2AMEN1ALDH1A1PAM | |
| Glutamine SCHEMBL18408962 | 0.91 | KMT2A (0.49) | MAPTKMT2ACYP1A2PAMALOX15 | |
| SCHEMBL346381 | 0.90 | DGKA (0.50) | DGKAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL336371 | 0.90 | DGKA (0.50) | DGKAMAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981328-B1 | COMPOSITION FORMING AN EMULSION FOR A TAXOID COMPOUND | SONUS PHARMA INC (US) | 2007-03-14 | — | — | EP | disclosed |
| US-7030155-B2 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. (US) | 2006-04-18 | — | — | US | disclosed |
| US-6982282-B2 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | disclosed |
| US-20050142189-A1 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| US-20040202712-A1 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. | 2004-10-14 | — | — | US | disclosed |
| US-20040053993-A1 | Compositions of tocol-soluble therapeutics | SONUS PHARMACEUTICALS, INC. | 2004-03-18 | — | — | US | disclosed |
| US-6667048-B1 | Pharmaceutical composition comprising taxoid, taxane or taxine as chemotherapeutic agent, alpha-tocopherol, tocopherol polyethylene glycol succinate, and aqueous phase, in form of emulsion or microemulsion with drug in oil phase | SONUS PHARMACEUTICALS, INC. | 2003-12-23 | — | — | US | disclosed |
| US-6660286-B1 | Tocopherol as primary solvent and tocopherol polyethylene glycol succinate as secondary solvent; Vitamin E | SONUS PHARMACEUTICALS, INC. | 2003-12-09 | — | — | US | disclosed |
| US-20030170279-A1 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. | 2003-09-11 | — | — | US | disclosed |
| US-20030147959-A1 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. | 2003-08-07 | — | — | US | disclosed |
| US-6479540-B1 | Compositions of tocol-soluble therapeutics | SONUS PHARMACEUTICALS, INC. | 2002-11-12 | — | — | US | disclosed |
| US-6458373-B1 | Emulsion vehicle for poorly soluble drugs | SONUS PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| EP-1216026-A1 | COMPOSITIONS OF TOCOL-SOLUBLE THERAPEUTICS | SONUS PHARMACEUTICALS, INC. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2002026208-A2 | EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS | SONUS PHARMACEUTICALS, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
| EP-1185301-A1 | EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS | SONUS PHARMACEUTICALS, INC. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001022937-A1 | COMPOSITIONS OF TOCOL-SOLUBLE THERAPEUTICS | SONUS PHARMACEUTICALS, INC. (US) | 2001-04-05 | — | — | WO | disclosed |
| WO-2000071163-A1 | EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS | SONUS PHARMACEUTICALS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| EP-0981328-A1 | EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS | SONUS PHARMACEUTICALS, INC. (US) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998030205-A9 | EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS | — | 1998-12-30 | — | — | WO | disclosed |
| WO-1998030205-A1 | EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS | SONUS PHARMACEUTICALS, INC. (US) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050142189-A1 | Emulsion vehicle for poorly soluble drugs | TTPA, SUCNR1, SDHA | DGKA 952/4885MAPT 1200/4885LMNA 1557/4885 |
| US-20030170279-A1 | Emulsion vehicle for poorly soluble drugs | TTPA, SUCNR1, SDHA | DGKA 1232/4885MAPT 1423/4885LMNA 1950/4885 |
| US-20030147959-A1 | Emulsion vehicle for poorly soluble drugs | TTPA, SUCNR1, SDHB | DGKA 1905/4885MAPT 2419/4885LMNA 2098/4885 |
| US-20040053993-A1 | Compositions of tocol-soluble therapeutics | TTPA, SLC25A13, PCTP | DGKA 1137/4885MAPT 1744/4885LMNA 4062/4885 |
| US-20040202712-A1 | Emulsion vehicle for poorly soluble drugs | TTPA, SUCNR1, SELE | DGKA 1316/4885MAPT 1385/4885LMNA 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.