Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.41 |
| ▸ | RXRB | P28702 | 12/20 | 0.41 |
| ▸ | RXRG | P48443 | 11/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757995 | 0.85 | RXRA (0.52) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL8839361 | 0.83 | RXRA (0.48) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL8839144 | 0.81 | RXRA (0.47) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL8839151 | 0.80 | RXRA (0.46) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL7876781 | 0.79 | RXRA (0.44) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL8100597 | 0.79 | RXRA (0.44) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL8100803 | 0.79 | RXRA (0.44) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL7885957 | 0.78 | RXRA (0.42) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL8102470 | 0.77 | RXRA (0.43) | RXRARXRBRXRGCYP3A4RARA | |
| SCHEMBL7883330 | 0.75 | RXRA (0.40) | RXRARXRBRXRGCYP3A4RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661260-B1 | New bi-aromatic compounds derived from amides pharmaceutical compositions and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1997-03-12 | — | — | EP | claimed |