Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560839 | 0.90 | TSHR (0.38) | TSHRHPGDDNM1DGKAALDH1A1 | |
| SCHEMBL8558720 | 0.89 | TSHR (0.41) | TSHRHPGDDNM1DGKAALDH1A1 | |
| SCHEMBL8559074 | 0.87 | DGKA (0.34) | TSHRDNM1DGKAALDH1A1MAPT | |
| SCHEMBL8749132 | 0.83 | DNM1 (0.49) | DNM1ALDH1A1MAPTTHRB | |
| SCHEMBL8590382 | 0.82 | TSHR (0.41) | TSHRDNM1MGLL | |
| SCHEMBL9976373 | 0.81 | — | — | |
| SCHEMBL5709243 | 0.80 | — | — | |
| SCHEMBL8826136 | 0.79 | TSHR (0.61) | TSHRALDH1A1MAPK1ATMRECQL | |
| SCHEMBL8560501 | 0.76 | KMT2A (0.48) | TSHRALDH1A1MAPTRECQLL3MBTL1 | |
| SCHEMBL12120249 | 0.76 | DGKA (0.55) | TSHRHPGDDNM1DGKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679738-A | Aqueous polymeric emulsions incorporating polymerized units of michael adducts of N-vinylformamide | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5672731-A | USEFUL AS MONOMERS IN FREE RADICAL POLYMERIZATION, PARTICULARLY AS COMPONENTS OF PHOTOCURABLE COATINGS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0683183-B1 | Michael adducts of n-vinylformamide and acrylic and methacrylic esters | AIR PROD & CHEM (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0763522-A1 | N-vinylformamide/alkyl acrylate michael adducts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0683183-A1 | Michael adducts of n-vinylformamide and acrylic and methacrylic esters | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5463110-A | A 3-(N-vinylformamido)propionate in photocurable coatings; reactive diluents; solvents; hydrophobic; glass transition temperatures; kinetics | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-10-31 | — | — | US | disclosed |