Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560839 | 0.98 | TSHR (0.38) | TSHRALDH1A1CYP3A4DNM1HTR2C | |
| SCHEMBL8559074 | 0.91 | DGKA (0.34) | TSHRALDH1A1DNM1DGKAMAPT | |
| SCHEMBL8749111 | 0.89 | TSHR (0.46) | TSHRALDH1A1DNM1HTR2CNAAA | |
| SCHEMBL8590382 | 0.86 | TSHR (0.41) | TSHRDNM1 | |
| SCHEMBL9976373 | 0.85 | — | — | |
| SCHEMBL5709243 | 0.84 | — | — | |
| SCHEMBL8749132 | 0.83 | DNM1 (0.49) | ALDH1A1CYP3A4DNM1MAPTNPSR1 | |
| Potassium Ion SCHEMBL6405216 | 0.82 | MEN1 (0.31) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7070145 | 0.81 | CYP1A2 (0.40) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL8665088 | 0.81 | TSHR (0.46) | TSHRALDH1A1CYP3A4MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712411-A | N-vinylformamidopropionates and process for their synthesis | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0779272-A1 | N-Vinylformamidopropionates, process for their synthesis and their use as chain extenders and crosslinking agents | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-06-18 | — | — | EP | disclosed |