Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974635 | 0.82 | MAPK1 (0.30) | — | |
| SCHEMBL1219320 | 0.80 | — | — | |
| SCHEMBL6984958 | 0.80 | INMT (0.34) | — | |
| SCHEMBL24796261 | 0.79 | — | — | |
| SCHEMBL3469140 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL4968832 | 0.77 | ALDH1A1 (0.49) | — | |
| SCHEMBL6686488 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL4974655 | 0.75 | MAPK1 (0.31) | — | |
| SCHEMBL9698433 | 0.74 | MGLL (0.44) | ALOX15 | |
| SCHEMBL20060571 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2010045008-A1 | AMIDES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |