Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCK1 | P16333 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749414 | 0.92 | NQO2 (0.52) | NQO2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8403348 | 0.78 | ALDH1A1 (0.45) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10553377 | 0.76 | NQO2 (0.64) | NQO2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8404861 | 0.76 | KDM4E (0.54) | NQO2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL8404114 | 0.75 | PIK3CG (0.60) | KDM4EMAPTALDH1A1TDP1CYP1A2 | |
| SCHEMBL8399923 | 0.75 | ALDH1A1 (0.56) | NQO2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8749540 | 0.75 | TRPA1 (0.44) | KDM4EMAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL2756741 | 0.74 | NQO2 (0.85) | NQO2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9927345 | 0.74 | NQO2 (0.85) | NQO2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL21131352 | 0.72 | NQO2 (0.81) | NQO2KDM4EMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675881-B1 | Use of benzotriazines as PLA2-Inhibitors and new benzotriazines | BOEHRINGER MANNHEIM GMBH (DE) | 1997-03-19 | — | — | EP | disclosed |