Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 6/20 | 0.79 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.63 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.63 |
| ▸ | NSD2 | O96028 | 4/20 | 0.63 |
| ▸ | SETD7 | Q8WTS6 | 4/20 | 0.63 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.63 |
| ▸ | NNMT | P40261 | 3/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.63 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.63 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.63 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.63 |
| ▸ | INMT | O95050 | 2/20 | 0.63 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.63 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.63 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.63 |
| ▸ | FASN | P49327 | 2/20 | 0.63 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.63 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.63 |
| ▸ | PNMT | P11086 | 1/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583457 | 0.88 | MARS1 (1.00) | MARS1DOT1LCARM1NSD2SETD7 | |
| SCHEMBL3014292 | 0.88 | MARS1 (1.00) | MARS1DOT1LCARM1NSD2SETD7 | |
| SCHEMBL5582866 | 0.87 | MARS1 (0.84) | MARS1DOT1LCARM1NSD2SETD7 | |
| Sulfuric Acid SCHEMBL28535358 | 0.85 | MARS1 (0.93) | MARS1DOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL27500408 | 0.84 | MARS1 (0.77) | MARS1DOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL3014288 | 0.84 | MARS1 (0.77) | MARS1DOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL3014297 | 0.84 | MARS1 (0.77) | MARS1DOT1LCARM1NSD2SETD7 | |
| SCHEMBL4297538 | 0.83 | MARS1 (0.73) | MARS1DOT1LCARM1NSD2SETD7 | |
| Racemethionine SCHEMBL28493813 | 0.83 | MARS1 (0.75) | MARS1DOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL27683410 | 0.83 | MARS1 (0.75) | MARS1DOT1LCARM1NSD2SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763129-A1 | DNA ENCODING CEPHAMYCIN BIOSYNTHESIS LATE ENZYMES | MERCK & CO. INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995029253-A1 | DNA ENCODING CEPHAMYCIN BIOSYNTHESIS LATE ENZYMES | MERCK & CO., INC. (US) | 1995-11-02 | — | — | WO | disclosed |