Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 6/20 | 0.93 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.63 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.63 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.63 |
| ▸ | NSD2 | O96028 | 3/20 | 0.63 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.63 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.63 |
| ▸ | FASN | P49327 | 2/20 | 0.63 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.63 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.63 |
| ▸ | INMT | O95050 | 2/20 | 0.63 |
| ▸ | NNMT | P40261 | 2/20 | 0.63 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.63 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.63 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.63 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.63 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.63 |
| ▸ | PNMT | P11086 | 1/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583457 | 0.97 | MARS1 (1.00) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL3014292 | 0.97 | MARS1 (1.00) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL28544526 | 0.95 | MARS1 (0.86) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL28606779 | 0.92 | MARS1 (0.81) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL28606778 | 0.89 | MARS1 (0.76) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL5582866 | 0.88 | MARS1 (0.84) | MARS1DOT1LCARM1EHMT2NSD2 | |
| Adenosine SCHEMBL28535357 | 0.88 | MARS1 (0.72) | MARS1DOT1LCARM1EHMT2NSD2 | |
| Adenosine SCHEMBL28544361 | 0.88 | MARS1 (0.72) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL28544523 | 0.86 | MARS1 (0.75) | MARS1DOT1LCARM1EHMT2NSD2 | |
| SCHEMBL6408975 | 0.86 | MARS1 (0.80) | MARS1DOT1LCARM1EHMT2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341508-B | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-112341508-A | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-1935825-A | Method for preparing S-adenosine-L-methionine sulfate | UNIV ZHEJIANG (CN) | 2007-03-28 | — | — | CN | claimed |
| CN-112341508-B | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-112341508-A | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-02-09 | — | — | CN | disclosed |