Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRY1 | Q16526 | 1/20 | 0.41 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877971 | 0.78 | MMP2 (0.52) | MMP2MMP9KMT2AALDH1A1HPGD | |
| SCHEMBL876635 | 0.78 | MMP2 (0.52) | MMP2MMP9KMT2AALDH1A1HPGD | |
| SCHEMBL1380883 | 0.77 | MMP2 (0.54) | MMP2MMP9ADAMTS5 | |
| SCHEMBL873973 | 0.76 | KDM4E (0.42) | MMP2MMP9ALDH1A1HSD17B10MAPT | |
| SCHEMBL877478 | 0.74 | GPR139 (0.50) | MMP2MMP9KMT2AALDH1A1HPGD | |
| SCHEMBL1377157 | 0.74 | MMP2 (0.52) | MMP2MMP9ADAMTS5 | |
| SCHEMBL1380422 | 0.73 | MMP2 (0.54) | MMP2MMP9ADAMTS5 | |
| SCHEMBL1380421 | 0.73 | MMP2 (0.54) | MMP2MMP9ADAMTS5 | |
| SCHEMBL1378295 | 0.72 | MMP2 (0.54) | MMP2MMP9ADAMTS5LMNAKDM4E | |
| SCHEMBL1378296 | 0.72 | MMP2 (0.54) | MMP2MMP9ADAMTS5LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |