Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873568 | 0.78 | GPR139 (0.44) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL874425 | 0.78 | MMP2 (0.48) | MMP2MMP3MMP9MMP13 | |
| SCHEMBL874957 | 0.76 | CRY1 (0.41) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL874812 | 0.75 | GPR139 (0.46) | KDM4ESMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL877441 | 0.73 | GPR139 (0.44) | KDM4EMAPTMMP1MMP2MMP3 | |
| SCHEMBL876635 | 0.70 | MMP2 (0.52) | KDM4EHPGDALDH1A1MMP1MMP2 | |
| SCHEMBL877971 | 0.70 | MMP2 (0.52) | KDM4EHPGDALDH1A1MMP1MMP2 | |
| SCHEMBL874766 | 0.69 | GPR139 (0.39) | KDM4ESMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL4059596 | 0.68 | MMP2 (0.47) | MAPTSMN1; SMN2MMP2MMP9 | |
| SCHEMBL877592 | 0.67 | MMP2 (0.41) | ALDH1A1MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |