SCHEMBL8749786

SCHEMBL8749786

C=Cc1ccc(C(S)c2ccccc2C(=O)ON2C(=O)CCC2=O)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.32
HSD17B2 P37059 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8341133 0.75 KDM4E (0.39) MGLL
SCHEMBL19474889 0.73 KMT2A (0.55) MGLL
SCHEMBL723217 0.73 ALDH1A1 (0.35) MGLL
SCHEMBL8749795 0.72 KMT2A (0.40)
SCHEMBL9189639 0.71 MGLL (0.34) MGLL
SCHEMBL9191999 0.68 KMT2A (0.32) MGLL
SCHEMBL14335797 0.68 KMT2A (0.38) MGLL
SCHEMBL5303474 0.67 ALDH1A1 (0.48) MGLL
SCHEMBL8540066 0.67 TSHR (0.50)
SCHEMBL21160109 0.66 MAPK1 (0.40) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496473-B1 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1997-03-26 EP claimed
EP-0496473-A2 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP claimed