Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203624 | 0.87 | UCHL1 (0.40) | L3MBTL1HCRTR1HCRTR2PTGESUCHL1 | |
| SCHEMBL883263 | 0.87 | UCHL1 (0.40) | L3MBTL1HCRTR1HCRTR2PTGESUCHL1 | |
| SCHEMBL12406109 | 0.86 | HCRTR1 (0.46) | HCRTR1HCRTR2CHEK2USP30 | |
| SCHEMBL28743816 | 0.86 | UCHL1 (0.44) | L3MBTL1HCRTR1HCRTR2PTGESUCHL1 | |
| SCHEMBL14743583 | 0.85 | GABRG2 (0.39) | L3MBTL1PTGESUCHL1NPC1RAB9A | |
| SCHEMBL14743582 | 0.85 | GABRG2 (0.39) | L3MBTL1PTGESUCHL1NPC1RAB9A | |
| SCHEMBL570675 | 0.84 | HCRTR1 (0.41) | HCRTR1HCRTR2PTGESCHEK2 | |
| SCHEMBL18071565 | 0.84 | HSD11B1 (0.38) | HCRTR1HCRTR2PTGESCHEK2UCHL1 | |
| SCHEMBL570674 | 0.84 | HCRTR1 (0.41) | HCRTR1HCRTR2PTGESCHEK2 | |
| SCHEMBL570673 | 0.84 | HCRTR1 (0.41) | HCRTR1HCRTR2PTGESCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |