Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502263 | 0.86 | HDAC2 (0.68) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL15434970 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14859224 | 0.81 | ALDH1A1 (0.77) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9529391 | 0.79 | RAB9A (0.72) | ALDH1A1ALOX12MEN1KMT2AMAPT | |
| SCHEMBL21357791 | 0.79 | ALDH1A1 (0.83) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23068164 | 0.78 | ALDH1A1 (0.83) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12069268 | 0.77 | ALDH1A1 (0.81) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23068177 | 0.77 | ALDH1A1 (0.81) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12069271 | 0.77 | ALDH1A1 (0.81) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14859923 | 0.77 | ALDH1A1 (0.81) | ALDH1A1ALOX12CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672712-A | ANTIAGGLOMERANTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0765875-A1 | THIAZOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1997-04-02 | — | — | EP | disclosed |