Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980534 | 0.82 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA3 | |
| SCHEMBL29712359 | 0.82 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA3 | |
| SCHEMBL3978671 | 0.82 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA3 | |
| SCHEMBL3978681 | 0.82 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA3 | |
| SCHEMBL13844404 | 0.69 | PRMT5 (0.61) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL15828310 | 0.68 | P2RX1 (0.63) | ADORA1PDE4DPDE3A | |
| SCHEMBL15828228 | 0.68 | P2RX1 (0.63) | ADORA1PDE4DPDE3A | |
| SCHEMBL31725331 | 0.66 | AHCY (0.53) | PRMT5WDR77AHCYHSP90B1ADORA3 | |
| SCHEMBL21015672 | 0.66 | AHCY (0.50) | AHCYADORA2B | |
| SCHEMBL28030977 | 0.64 | PRMT5 (0.57) | PRMT5WDR77AHCYHSP90B1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765400-A1 | SCREEN FOR INHIBITORS OF CHITINASE | AMERICAN CYANAMID COMPANY (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995034678-A1 | SCREEN FOR INHIBITORS OF CHITINASE | AMERICAN CYANAMID COMPANY (US) | 1995-12-21 | — | — | WO | disclosed |