SCHEMBL3980534

SCHEMBL3980534

Nc1ncnc2c1ncn2C1OC(F)(COS(N)(=O)=O)C(O)C1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 1/20 0.54
▸ WDR77 Q9BQA1 1/20 0.54
▸ AHCY P23526 7/20 0.52
▸ HSP90B1 P14625 3/20 0.51
▸ ADORA2A P29274 2/20 0.51
▸ ADORA2B P29275 2/20 0.51
▸ HIF1A Q16665 1/20 0.51
▸ TMEM97 Q5BJF2 1/20 0.51
▸ SIGMAR1 Q99720 1/20 0.51
▸ HSP90AA1 P07900 1/20 0.49
▸ DPP4 P27487 1/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ SLC28A1 O00337 1/20 0.49
▸ MAP3K7 O43318 1/20 0.49
▸ SLC28A2 O43868 1/20 0.49
▸ GAPDH P04406 1/20 0.49
▸ ADORA3 P0DMS8 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ ADORA1 P30542 1/20 0.49
▸ STAT6 P42226 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3978671 1.00 PRMT5 (0.54) PRMT5WDR77AHCYHSP90B1ADORA2A
SCHEMBL3978681 1.00 PRMT5 (0.54) PRMT5WDR77AHCYHSP90B1ADORA2A
SCHEMBL29712359 1.00 PRMT5 (0.54) PRMT5WDR77AHCYHSP90B1ADORA2A
SCHEMBL13844404 0.84 PRMT5 (0.61) PRMT5WDR77AHCYADORA2AADORA2B
Nonactin SCHEMBL8750347 0.82 PRMT5 (0.44) PRMT5WDR77AHCYHSP90B1ADORA2A
SCHEMBL15828310 0.81 P2RX1 (0.63) ADORA1SMN1; SMN2
SCHEMBL15828228 0.81 P2RX1 (0.63) ADORA1SMN1; SMN2
SCHEMBL31725331 0.78 AHCY (0.53) PRMT5WDR77AHCYHSP90B1ADORA2A
SCHEMBL21015672 0.78 AHCY (0.50) AHCYADORA2BSLC28A1SLC28A2
SCHEMBL25390968 0.78 ADORA3 (0.57) PRMT5WDR77AHCYADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160158261-A1 Antibiotic Kit and Composition and Uses Thereof FOAMIX LTD. (IL) 2016-06-09 — — US claimed
US-9211259-B2 Antibiotic kit and composition and uses thereof FOAMIX PHARMACEUTICALS LTD. (IL) 2015-12-15 — — US claimed
EP-1919449-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF Foamix Ltd. (IL) 2008-05-14 — — EP claimed
WO-2007099396-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF FOAMIX LTD. (US) 2007-09-07 — — WO claimed
US-20060269485-A1 Antibiotic kit and composition and uses thereof FOAMIX LTD. (IL) 2006-11-30 — — US claimed
US-20260109675-A1 COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCER MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-04-23 — — US disclosed
US-20260103696-A1 COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCER MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-04-16 — — US disclosed
EP-4674476-A1 MAGNETIC FIELD VARIATION THERAPY FOR ENHANCING THERAPEUTIC AND DISINFECTION APPLICATIONS Azyro SA (LU) 2026-01-07 — — EP disclosed
US-12496310-B2 Compositions and methods for adoptive cell therapy MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-12-16 — — US disclosed
EP-3802850-B1 DEVICES AND SYSTEMS FOR GASTROINTESTINAL MICROBIOME DETECTION AND MANIPULATION BT BIDCO INC (US) 2025-11-19 — — EP disclosed
EP-3645561-B1 COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCER MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-05-07 — — EP disclosed
US-20250082265-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT BT BIDCO, INC. 2025-03-13 — — US disclosed
EP-0129285-B1 PENETRATING TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING N-(2-HYDROXYETHYL)PYRROLIDONE THE PROCTER & GAMBLE COMPANY (US) 1991-05-15 — — EP disclosed
US-4900407-A Method for deoxygenation of alcohols YAMASA SHOYU KABUSHIKI KAISHA (JP) 1990-02-13 — — US disclosed
EP-0238672-A1 PROCESS FOR DEOXIDIZING ALCOHOL Yamasa Shoyu Kabushiki Kaisha (JP) 1987-09-30 — — EP disclosed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 — — US disclosed
US-4537776-A PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS THE PROCTER & GAMBLE COMPANY (US) 1985-08-27 — — US disclosed
EP-0129285-A2 Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl)pyrrolidone THE PROCTER & GAMBLE COMPANY (US) 1984-12-27 — — EP disclosed
EP-0129284-A2 Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one THE PROCTER & GAMBLE COMPANY (US) 1984-12-27 — — EP disclosed
US-3928319-A 4 -Fluoro nucleosides, novel intermediates and methods of preparing same SYNTEX INC 1975-12-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103696-A1 COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCER CCRL2, CCR3, LY6K PRMT5 3522/4885WDR77 395/4885AHCY 1098/4885
US-12496310-B2 Compositions and methods for adoptive cell therapy HAVCR2, CD4, CCR1 PRMT5 3921/4885WDR77 1819/4885AHCY 174/4885
US-20250082265-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT TPMT, FABP2, SLC10A2 PRMT5 3166/4885WDR77 3872/4885AHCY 241/4885
US-20260109675-A1 COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCER IL2RA, CCR3, CD4 PRMT5 3295/4885WDR77 1101/4885AHCY 1148/4885
US-20160158261-A1 Antibiotic Kit and Composition and Uses Thereof KIT, RAB5IF, CUTA PRMT5 3835/4885WDR77 400/4885AHCY 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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