Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | AHCY | P23526 | 7/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978671 | 1.00 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA2A | |
| SCHEMBL29712359 | 1.00 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA2A | |
| SCHEMBL3980534 | 1.00 | PRMT5 (0.54) | PRMT5WDR77AHCYHSP90B1ADORA2A | |
| SCHEMBL13844404 | 0.84 | PRMT5 (0.61) | PRMT5WDR77AHCYADORA2AADORA2B | |
| Nonactin SCHEMBL8750347 | 0.82 | PRMT5 (0.44) | PRMT5WDR77AHCYHSP90B1ADORA2A | |
| SCHEMBL15828310 | 0.81 | P2RX1 (0.63) | ADORA1SMN1; SMN2 | |
| SCHEMBL15828228 | 0.81 | P2RX1 (0.63) | ADORA1SMN1; SMN2 | |
| SCHEMBL31725331 | 0.78 | AHCY (0.53) | PRMT5WDR77AHCYHSP90B1ADORA2A | |
| SCHEMBL21015672 | 0.78 | AHCY (0.50) | AHCYADORA2BSLC28A1SLC28A2 | |
| SCHEMBL25390968 | 0.78 | ADORA3 (0.57) | PRMT5WDR77AHCYADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058800-A2 | SYNTHESIS OF NUCLEOSIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-05-07 | — | — | WO | disclosed |