SCHEMBL8750386

SCHEMBL8750386

COC(C)c1cc(C)ccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 3/20 0.38
TRPA1 O75762 1/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A2 P23975 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
ACHE P22303 1/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.34
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
HSD11B1 P28845 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750521 0.84 ALDH1A1 (0.39) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL8750414 0.83 TRPA1 (0.42) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL21373872 0.80 ALDH1A1 (0.39) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL22897719 0.79 CYP3A4 (0.46) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL15854044 0.79 SLC6A4 (0.33) SLC6A2POLB
SCHEMBL30165955 0.77 LMNA (0.54) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL11882816 0.77 ALDH1A1 (0.44) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL598624 0.77 LMNA (0.54) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL12203806 0.75 LMNA (0.39) ALDH1A1TDP1LMNATRPA1CHRM1
SCHEMBL18579593 0.75 ALDH1A1 (0.48) ALDH1A1TDP1LMNATRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523697-B1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS (JP) 1997-04-02 EP disclosed
US-5447901-A Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid MITSUI TOATSU CHEMICAL, INC. (JP) 1995-09-05 US disclosed
US-5376615-A Pressure sensitive elements containing a salicylic acid resin and a phenolic resin MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-12-27 US disclosed
EP-0523697-A1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed
US-5023366-A Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-06-11 US disclosed
EP-0268878-A2 Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-01 EP disclosed