Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28272294 | 0.98 | ERN1 (0.56) | ERN1HIF1ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL419690 | 0.86 | ERN1 (0.58) | ERN1CYP2C19ALDH1A1PIM1MEN1 | |
| SCHEMBL4879192 | 0.83 | ERN1 (0.51) | ERN1HIF1ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL12678851 | 0.81 | HIF1A (0.39) | ERN1HIF1ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL12813802 | 0.81 | ERN1 (0.47) | ERN1HSD17B10ALDH1A1ALOX15TDP1 | |
| SCHEMBL28311710 | 0.81 | ERN1 (0.47) | ERN1HIF1ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2477063 | 0.81 | ERN1 (0.52) | ERN1CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29785434 | 0.81 | ERN1 (0.47) | ERN1HIF1ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL727292 | 0.80 | TSHR (0.73) | HIF1ACYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29467330 | 0.79 | ALOX5 (0.49) | ERN1HIF1ACYP2C9CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113856762-A | High-poly Salen cobalt catalyst, preparation method and application | 华今(山东)新材料科技有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-109134298-B | Platinum dimer Schiff base complex and preparation method and application thereof | 台州学院 | 2021-03-16 | — | — | CN | claimed |
| CN-106632489-B | A kind of platinum green light material and preparation method thereof containing Schiff base ligand | 台州学院 | 2019-04-30 | — | — | CN | claimed |
| CN-109134298-A | A kind of preparation and application of dimerization schiff bases platinum complex | 台州学院 | 2019-01-04 | — | — | CN | claimed |
| CN-117101726-A | Metal complex catalyst and preparation method of 2, 4-trimethyl adipic acid | 山东新和成维生素有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-109970755-B | Synthesis of substituted salicylaldehyde derivatives | 沙特阿美技术公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113856762-A | High-poly Salen cobalt catalyst, preparation method and application | 华今(山东)新材料科技有限公司 | 2021-12-31 | — | — | CN | disclosed |
| US-11124522-B2 | Chemosensor and a method of detecting palladium ions | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2021-09-21 | — | — | US | disclosed |
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| CN-109134298-B | Platinum dimer Schiff base complex and preparation method and application thereof | 台州学院 | 2021-03-16 | — | — | CN | disclosed |
| CN-109134298-B | Platinum dimer Schiff base complex and preparation method and application thereof | 台州学院 | 2021-03-16 | — | — | CN | disclosed |
| EP-0343866-A1 | Aminophenol derivatives | ICI AMERICAS INC. (US) | 1989-11-29 | — | — | EP | disclosed |
| CN-88103112-A | AMIDES | — | 1988-12-28 | — | — | CN | disclosed |
| EP-0293171-A1 | Pyrazinamide derivatives | ICI AMERICAS INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0293170-A1 | Aminomethylphenolic pyrazines, their preparation and use | ICI AMERICAS INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4221790-A | Substituted 2,2-dioxo-1,2,3-benzoxathiazines | MERCK & CO., INC. (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0011654-A1 | Nuclear substituted 2-hydroxymethane-sulfamic acids and pharmaceutical compositions | MERCK & CO. INC. (US) | 1980-06-11 | — | — | EP | disclosed |
| US-4166177-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1979-08-28 | — | — | US | disclosed |
| US-4159279-A | SALURETIC-DIURETICS, DERMATOLOGICAL DISORDERS, ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124522-B2 | Chemosensor and a method of detecting palladium ions | DDT, PDCD1, PDCD10 | ERN1 4470/4885HIF1A 3114/4885CYP2C9 2248/4885 |
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | ITGB1, ITGAV, ITGA1 | ERN1 3452/4885HIF1A 714/4885CYP2C9 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.