SCHEMBL727292

SCHEMBL727292

CC(C)(C)c1cc(Br)c(O)c(Br)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.73
HSD17B10 Q99714 4/20 0.73
HIF1A Q16665 3/20 0.73
ALOX15 P16050 3/20 0.73
TDP1 Q9NUW8 3/20 0.73
ALDH1A1 P00352 3/20 0.73
ALOX12 P18054 2/20 0.73
CYP3A4 P08684 2/20 0.73
HPGD P15428 2/20 0.73
CASP1 P29466 1/20 0.73
RECQL P46063 1/20 0.73
CYP2C9 P11712 3/20 0.60
CYP2C19 P33261 3/20 0.60
CYP1A2 P05177 2/20 0.60
CYP2D6 P10635 2/20 0.60
CHEK1 O14757 1/20 0.54
DAPK3 O43293 1/20 0.54
RET P07949 1/20 0.54
PDGFRB P09619 1/20 0.54
PIM1 P11309 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065615 0.97 TSHR (0.70) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL2476258 0.88 TSHR (0.58) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL68929 0.88 ALOX15 (0.58) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL3073021 0.86 TSHR (0.56) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL814586 0.84 TSHR (0.54) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL5173922 0.84 TSHR (1.00) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL18647 0.84 TSHR (1.00) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL1477247 0.84 TSHR (0.73) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL9512821 0.81 GABRA1 (0.50) TSHRHSD17B10HIF1AALOX15TDP1
SCHEMBL11777742 0.81 CYP2C19 (0.67) TSHRHSD17B10HIF1AALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499455-B2 Process for the selective dimerisation of ethylene to 1-butene IFP Energies Nouvelles (FR) 2016-11-22 US claimed
US-8575239-B2 Curing composition and cured product prepared by using the same LG CHEM, LTD. (KR) 2013-11-05 US claimed
JP-2011525198-A 2011-09-15 JP claimed
US-20100286302-A1 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2010-11-11 US claimed
EP-2231781-A2 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME LG Chem, Ltd. (KR) 2010-09-29 EP claimed
WO-2009084861-A2 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME LG CHEM, LTD. (KR) 2009-07-09 WO claimed
US-6903042-B2 Catalytic composition and process for oligomerizing ethylene, in particular to 1-hexene INSTITUT FRANCAIS DU PETROLE (FR) 2005-06-07 US claimed
US-4172960-A ETHERIFICATION, DEETHERIFICATION, DIALKYLATION FISONS LIMITED (GB) 1979-10-30 US claimed
JP-60097971-A None JP disclosed
US-20250122152-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-04-17 US disclosed
WO-2025068943-A1 KAT6 INHIBITORS BEIGENE SWITZERLAND GMBH (CH) 2025-04-03 WO disclosed
US-20240239725-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies Nouvelles (FR) 2024-07-18 US disclosed
EP-4347542-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies nouvelles (FR) 2024-04-10 EP disclosed
CN-117693496-A Oligomerization process in a reactor having a variable diameter zone comprising a step of recycling pre-cooled solvent IFP 新能源公司 2024-03-12 CN disclosed
EP-0885656-A1 Catalytic composition and ethylene oligomerization, especially in 1-butene and/or 1-hexene Institut Français du Pétrole (FR) 1998-12-23 EP disclosed
US-4588835-A Process for preparing alkoxyphenols OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1986-05-13 US disclosed
JP-S6097971-A PRODUCTION OF NOVEL 2,6-DIBROMO-4-TERT-BUTYL-PHENYL GLYCIDYL ETHER AND ITS PRODUCTION SANYO KOKUSAKU PULP CO LTD 1985-05-31 JP disclosed
US-4172960-A ETHERIFICATION, DEETHERIFICATION, DIALKYLATION FISONS LIMITED (GB) 1979-10-30 US disclosed
US-4150068-A OLIGOMERIC POLYHALOPHOSPHATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-04-17 US disclosed
US-4004053-A FIREPROOFING ACRYLONITRILE POLYMERS CELANESE CORPORATION (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239725-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT PRPF40A, NSF, NOD2 TSHR 4442/4885HSD17B10 465/4885HIF1A 4398/4885
US-20250122152-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT7 TSHR 3646/4885HSD17B10 672/4885HIF1A 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.