Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165573 | 0.82 | PNMT (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7482558 | 0.79 | HTR3E (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8957794 | 0.73 | TSHR (0.43) | TSHRLMNANPC1ESR1ESR2 | |
| SCHEMBL1547384 | 0.72 | — | — | |
| SCHEMBL3194959 | 0.71 | HTR3E (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL861925 | 0.71 | MAPT (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8964884 | 0.71 | MAPT (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9638537 | 0.70 | NOS3 (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9480131 | 0.70 | TSHR (0.45) | TSHRLMNANPC1ALDH1A1MAPT | |
| SCHEMBL5144313 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552925-B1 | Equilibration of cyclic siloxanes with catalysts | DOW CORNING (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0552925-A2 | Equilibration of cyclic siloxanes with novel catalysts | DOW CORNING CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |